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Why "significant" results from tiny studies are inflated

A small, underpowered study finds a "significant" effect and reports a large estimate. A colleague argues that low power just means you usually miss real effects, so if you did find one, it must be solid.

Explain why a significant result from an underpowered study is systematically biased upward in magnitude, and what to do about it.

Your answer

This one is open-ended. Work it through, then check your reasoning against the full solution.

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